Antimicrobial Susceptibility of <i>Pasteurella multocida</i> Isolated from Sheep with Fibrinous Pneumonia

Abstract Ovine respiratory complex is a significant cause of death in sheep flocks, where Pasteurella multocida the most frequent microorganisms isolated from animals with pneumonia. There an urgent need to refine use different antimicrobials avoid problem antimicrobial resistance and optimize control this disease ovine livestock. The first step approaching gaining insight into susceptibility pathogens. This study evaluated vitro activity tildipirosin, gamithromycin, oxytetracycline, danofloxacin against strains fibrinous were incubated following Clinical Laboratory Standards Institute (CLSI) standard conditions also modified method by 25% supplementation serum. Minimum inhibitory concentrations (MIC) determined using broth microdilution technique. lowest MIC 90 under serum was obtained tildipirosin. Sheep significantly reduced values for strains. In brief, potency tildipirosine, increases when added culture media.